Polyarteritis nodosa (PAN): systemic features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Polyarteritis nodosa (PAN): systemic features. Intestinal infarction and necrosis, Gastric perforation. Fully referenced neurology checklist.

Gastrointestinal features

  • Intestinal infarction and necrosis
  • Gastric perforation
  • Intestinal perforation
  • Bowel gangrene
  • Gastrointestinal haemorrhage: haematemesis and melena
  • Pseudomembranous colitis
  • Pneumatosis intestinalis: gas in the bowel wall
  • Necrotising appendicitis
  • Retroperitoneal haemorrhage
  • Ascites

Hepatobiliary features

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Pancreatic features

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Dermatological features

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Ophthalmic features

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Renal features

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Genitourinary features

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Cardiac features

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Respiratory features

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ENT features

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Other features

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References

  1. Dewar CL, Bellamy N. Necrotizing mesenteric vasculitis after longstanding cutaneous polyarteritis nodosa. J Rheumatol 1992; 19:1308-1311.
  2. Tun M, Malik AK. Massive small bowel infarction and duodenal perforation due to abdominal polyarteritis nodosa: a case report. Malays J Pathol 1994; 16:75-78.
  3. Becker A, Mader R, Elias M, Lev A, Sayfan J. Duodenal necrosis as the presenting manifestation of polyarteritis nodosa. Clin Rheumatol 2002; 21:314-316.
  4. Gourgoutis GD, Paguirigan AA, Berzins T. Gastric perforation in polyarteritis nodosa. Report of a patient. Am J Dig Dis 1971; 16:171-177.
  5. Okada M, Konishi F, Sakuma K, Kanazawa K, Koiwai H, Kaizaki Y. Perforation of the sigmoid colon with ischemic change due to polyarteritis nodosa. J Gastroenterol 1999; 34:400-404.
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