Polyarteritis nodosa (PAN): management

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Polyarteritis nodosa (PAN): management. Full blood count, Urinalysis: for proteinuria and haematuria. Fully referenced neurology checklist.

Routine blood tests

  • Full blood count
  • Urinalysis: for proteinuria and haematuria
  • Erythrocyte sedimentation rate ESR)
  • C‐reactive protein (CRP)
  • Muscle enzymes
  • Liver function tests
  • Serum creatinine
  • Blood cultures

Viral tests

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Autoimmune tests

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Imaging tests

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Conventional treatments

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Emerging treatments

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References

  1. Pagnoux C, Seror R, Henegar C, et al. Clinical features and outcomes in 348 patients with polyarteritis nodosa: a systematic retrospective study of patients diagnosed between 1963 and 2005 and entered into the French Vasculitis Study Group Database. Arthritis Rheum 2010; 62:616-626.
  2. Howard T, Ahmad K, Swanson JA, Misra S. Polyarteritis nodosa. Tech Vasc Interv Radiol 2014; 17:247-251.
  3. Capuozzo M, Ottaiano A, Nava E, Cascone S, Fico R, Iaffaioli RV, Cinque C. Etanercept induces remission of polyarteritis nodosa: a case report. Front Pharmacol 2014; 5:122.
  4. Akiyama M, Kaneko Y, Takeuchi T. Tocilizumab for the treatment of polyarteritis nodosa: a systematic literature review. Ann Rheum Dis 2020 (Online ahead of print).
  5. Watanabe K, Rajderkar DA, Modica RF. A case of polyarteritis nodosa associated with vertebral artery vasculitis treated successfully with tocilizumab and cyclophosphamide. Case Rep Pediatr 2016; 2016:7987081.
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