Peripheral neuropathy (PN): blood investigations
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Peripheral neuropathy (PN): blood investigations. Full blood count (FBC), Renal and liver function tests. Fully referenced neurology checklist.
Baseline blood tests
- Full blood count (FBC)
- Renal and liver function tests
- Thyroid function test (TFT)
- Blood glucose
- Oral glucose tolerance test (OGTT)
- Vitamin B12
- Folate
Immunoglobulins: causes of raised IgM
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Immunoglobulins: causes of raised IgA and IgG
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Serum tests
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Autoantibodies
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Inflammatory markers
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Infection screen
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Common genetic tests
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Other tests
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References
- England JD, Gronseth GS, Franklin G, et al. Practice Parameter: evaluation of distal symmetric polyneuropathy: role of laboratory and genetic testing (an evidence-based review). Report of the American Academy of Neurology, American Association of Neuromuscular and Electrodiagnostic Medicine, and American Academy of Physical Medicine and Rehabilitation. Neurology 2009; 72:185-192.
- Burns TM, Mauermann ML. The evaluation of polyneuropathies. Neurology 2011; 76:S6-S13.
- Alport AR, Sander HW. Clinical approach to peripheral neuropathy: anatomic localization and diagnostic testing. Continuum (Minneap Minn) 2012; 18:13-38.
- Overell JR. Peripheral neuropathy: pattern recognition for the pragmatist. Pract Neurol 2011; 11:62-70.
- Karam C, Moshe-Lilie O, Chahin N, Ragole T, Medvedova E, Silbermann R. Diagnosis of paraproteinemic neuropathy: room for improvement. J Neurol Sci 2020; 415:116902.
