Periodic limb movements in sleep (PLMS)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Periodic limb movements in sleep (PLMS). Type I: spontaneous: worse in the early sleep period. Fully referenced neurology checklist.
Classification
- Type I: spontaneous: worse in the early sleep period
- Type II: secondary: uniformly spread throughout the sleep period
Risk genes: for type I PLMS
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Diagnostic criteria
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Clinical features
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Associated symptoms
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Associated neurological disorders
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Associated systemic disorders
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Potential drug triggers
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Possible complications
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Differential diagnosis
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Investigations
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Treatment
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Old synonym
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References
- Choi JW, Song JS, Lee YJ, Jeong DU. Periodic limb movements in sleep is associated with increased mortality. Psychiatry Investig 2017; 14:669-673.
- Natarajan R. Review of periodic limb movement and restless leg syndrome. J Postgrad Med 2010; 56:157-162.
- Winkelman JW, Blackwell T, Stone K, et al. Genetic associations of periodic limb movements of sleep in the elderly for the MrOS sleep study. Sleep Med 2015; 16:1360-1365.
- Moore H 4th, Winkelmann J, Lin L, Finn L, Peppard P, Mignot E. Periodic leg movements during sleep are associated with polymorphisms in BTBD9, TOX3/BC034767, MEIS1, MAP2K5/SKOR1, and PTPRD. Sleep 2014; 37:1535-1542.
- Stefani A, Heidbreder A, Hackner H, Högl B. Validation of a leg movements count and periodic leg movements analysis in a custom polysomnography system. BMC Neurol 2017; 17:42.
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