Parry Romberg syndrome (PRS): management

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Parry Romberg syndrome (PRS): management. White matter hyperintensities, Cerebral hemiatrophy, Encephalomalacia. Fully referenced neurology checklist.

Magnetic resonance imaging (MRI) brain: features

  • White matter hyperintensities
  • Cerebral hemiatrophy
  • Encephalomalacia
  • Cystic degeneration
  • Frontal lobe subcortical calcifications
  • Loss of cortical gyrations
  • Cortical thickening
  • Ventriculomegaly
  • Corpus callosum infarcts
  • Leptomeningeal thickening

Other investigations

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Treatment

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Synonyms

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References

  1. Tolkachjov SN, Patel NG, Tollefson MM. Progressive hemifacial atrophy: a review. Orphanet J Rare Dis 2015; 10:39.
  2. Wong M, Phillips CD, Hagiwara M, Shatzkes DR. Parry Romberg syndrome: 7 cases and literature review. Am J Neuroradiol 2015; 36:1355-1361. 
  3. Restivo DA, Milone P. Teaching NeuroImages: progressive facial hemiatrophy (Parry-Romberg syndrome) with ipsilateral cerebral hemiatrophy. Neurology 2010; 74(3):e11.

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