Paroxysmal kinesigenic dyskinesia (PKD): treatment

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Paroxysmal kinesigenic dyskinesia (PKD): treatment. Carbamazepine: the response is good in almost all cases. Fully referenced neurology checklist.

Drug treatments

  • Carbamazepine: the response is good in almost all cases
  • Acetazolamide
  • Phenytoin
  • Clonazepam
  • Triptans
  • Lacosamide

Non-drug treatments

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References

  1. Madhusudanan M, Bhatia KP, Balint B. Paroxysmal craniocervical dyskinesia as manifestation of frontal lobe epilepsy. Mov Disord 2011; 26:2580-2582.
  2. van Rootselaar A-F, van Westrum SS, Velis DN, Tijssen MAJ. The paroxysmal dyskinesias. Pract Neurol 2009; 9:102-109.
  3. Huang XJ, Wang T, Wang JL, et al.Paroxysmal kinesigenic dyskinesia: clinical and genetic analyses of 110 patients. Neurology 2015; 85:1546-1553. 
  4. Mathew T, Aroor S, Nadig R, Sarma GR. Lacosamide in paroxysmal kinesigenic dyskinesia. Mov Disord 2012; 27:801-802.

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