Parkinson’s disease (PD): poor prognostic factors
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Parkinson’s disease (PD): poor prognostic factors. Older age at onset, Male gender. Fully referenced neurology checklist.
Personal factors
- Older age at onset
- Male gender
- Women have worse drug-induced complications
Cognitive factors
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Parkinsonian factors
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Co-morbid factors
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Cerebrospinal fluid (CSF) factors
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Systemic factors
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Good prognostic factors for PD
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References
- Suchowersky O, Reich S, Perlmutter J, Zesiewicz T, Gronseth G, Weiner WJ. Practice parameter: diagnosis and prognosis of new onset Parkinson disease (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2006; 66:968-975.
- Poewe W. The natural history of Parkinson's disease. J Neurol 2006; 253 (Suppl 7):VII/2-VII/6.
- Georgiev D, Hamberg K, Hariz M, Forsgren L, Hariz GM. Gender differences in Parkinson's disease: a clinical perspective. Acta Neurol Scand 2017; 136:570-584.
- Picillo M, Nicoletti A, Fetoni V, Garavaglia B, Barone P, Pellecchia MT. The relevance of gender in Parkinson's disease: a review. J Neurol 2017; 264:1583-1607.
- Thomas GEC, Leyland LA, Schrag AE, Lees AJ, Acosta-Cabronero J, Weil RS. Brain iron deposition is linked with cognitive severity in Parkinson's disease. JNNP 2020; 91:418-425.
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