Osmotic demyelination disorders (ODD): clinical features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Osmotic demyelination disorders (ODD): clinical features. Central pontine myelinolysis (CPM): in the central basis pontis.

Types of ODD

  • Central pontine myelinolysis (CPM): in the central basis pontis
  • Extrapontine myelinolysis: in the thalamus, basal ganglia, cerebellum, and spinal cord

Neurological features

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Movement disorders

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Psychiatric features

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References

  1. Tan H, Onbaş O. Central pontine myelinolysis central pontine myelinolysis manifesting with massive myoclonus. Pediatr Neurol 2004; 31:64-66.
  2. Musana AK, Yale SH. Central pontine myelinolysis: case series and review. WMJ 2005; 104:56-60.
  3. Floris G, Di Stefano F, Melis R, Cherchi MV, Marrosu F. Isolated bipallidal lesions caused by extrapontine myelinolysis. Neurology 2013; 81:1722-1723.
  4. Jacob S, Gupta H, Nikolic D, Gundogdu B, Ong S. Central pontine and extrapontine myelinolysis: the great masquerader-an autopsy case report. Case Rep Neurol Med 2014; 2014:745347.
  5. Ahmad G, Vassallo J, Naqvi J, Khanna N. An unusual case of quadriparesis. BMJ 2013; 347:f5728.
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