Operative management of neuromuscular disorders drugs

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Operative management of neuromuscular disorders drugs. Continue anticholinesterase agents until anaesthesia. Fully referenced neurology checklist.

Preoperative anticholinesterase drug precautions

  • Continue anticholinesterase agents until anaesthesia
  • Convert oral to intravenous Pyridostigmine if needed
  • Convert oral Pyridostigmine to intravenous Neostigmine if needed

Preoperative immunosuppressant drug precautions

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Drugs to use with caution: neuromuscular junction (NMJ) disorders

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Drugs to use with caution: muscle channelopathies

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Drugs to use with caution: mitochondrial myopathies

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References

  1. van den Bersselaar LR, Heytens L, Silva HCA, et al. European Neuromuscular Centre consensus statement on anaesthesia in patients with neuromuscular disorders. Eur J Neurol 2022; 29:3486-3507.

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