Anaesthetic agents in neuromuscular disorders

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Anaesthetic agents in neuromuscular disorders. Use regional anesthesia whenever possible. Fully referenced neurology checklist.

General anaesthetic principles

  • Use regional anesthesia whenever possible
  • Consider total intravenous aneasthesia (TIVA)
  • Sedation and aneasthesia must be done in facilities with 24-hour care
  • Schedule neuromuscular patients as the first cases of the day
  • Consider the use of Suggamadex
  • Consider the perioperative risk of non-anaesthetic drugs

Anaesthetic risk considerations: sedatives

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Anaesthetic risk considerations: others

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Medical risk considerations

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References

  1. Racca F, Mongini T, Wolfler A, et al. Recommendations for anesthesia and perioperative management of patients with neuromuscular disorders. Minerva Anestesiol 2013; 79:419-433. 
  2. Katz JA, Murphy GS. Anesthetic consideration for neuromuscular diseases. Curr Opin Anaesthesiol 2017; 30:435-440.
  3. Baur CP, Schlecht R, Jurkat-Rott K, Georgieff M, Lehmann-Horn F. Anesthesia in neuromuscular disorders. Part 1: introduction. Anasthesiol Intensivmed Notfallmed Schmerzther 2002; 37:77-83. 
  4. van den Bersselaar LR, Heytens L, Silva HCA, et al. European Neuromuscular Centre consensus statement on anaesthesia in patients with neuromuscular disorders. Eur J Neurol 2022; 29:3486-3507.
  5. Sinclair JL, Reed PW. Risk factors for perioperative adverse events in children with myotonic dystrophy. Paediatr Anaesth 2009; 19:740-747. 
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