Oculogyric crisis (OGC)

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Oculogyric crisis (OGC). There is paroxysmal conjugate sustained eye deviation. Episodes last seconds to hours. Fully referenced neurology checklist.

Clinical features

  • There is paroxysmal conjugate sustained eye deviation
  • Episodes last seconds to hours
  • There is preserved consciousness
  • There may be preceding anxiety or discomfort
  • They may be triggered or worsened by emotional stress and fatigue
  • They may improve with rest and sleep

Associated movement disorders

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Associated autonomic features

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Associated psychiatric features

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Causes: medications

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Causes: others

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Differential diagnosis

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Treatment

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References

  1. Mahal P, Suthar N, Nebhinani N. Spotlight on oculogyric crisis: a review. Indian J Psychol Med 2021; 43:5-9.
  2. Solberg M, Koht J. Oculogyric crises. Tremor Other Hyperkinet Mov (N Y) 2017; 7:491.
  3. Rebelo Procaci V, da Hora RPC, Tonholo Silva TY, Barsottini OGP, Pedroso JL. Involuntary eye movements as a clue to diagnosis. Mov Disord Clin Pract 2025; 12:1662-1663.
  4. Koban Y, Ekinci M, Cagatay HH, Yazar Z. Oculogyric crisis in a patient taking metoclopramide. Clin Ophthalmol 2014; 8:567-569.
  5. Veerapandiyan A, Gallentine WB, Winchester SA, Baker J, Kansagra SM, Mikati MA. Oculogyric crises secondary to lamotrigine overdosage. Epilepsia 2011; 52:e4-e6.
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