New oral anticoagulants (NOACs): management of bleeding
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
New oral anticoagulants (NOACs): management of bleeding. There is no need for blood monitoring. Fully referenced neurology checklist.
General guidelines
- There is no need for blood monitoring
- There is no need for drug dose adjustments
- There are very few drug or food interactions
Control of bleeding
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Treatment of bleeding
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NOAC-specific management
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References
- Tendera M, Syzdol M, Parma Z. ARISTOTLE RE-LYs on the ROCKET. What's new in stroke prevention in patients with atrial fibrillation? Cardiol J 2012; 19:4-10.
- Agarwal MB, Verma S, Mahapatra M, et al. Balancing efficacy and bleeding risk in the prevention of stroke due to atrial fibrillation with newer oral anticoagulants. Indian J Hematol Blood Transfus 2012; 28:129-143.
- Christensen H, Cordonnier C, Kõrv J, et al. European Stroke Organisation guideline on reversal of oral anticoagulants in acute intracerebral haemorrhage. Eur Stroke J 2019; 4:294-306.
- Hemphill JC 3rd, Greenberg SM, Anderson CS, et al; American Heart Association Stroke Council; Council on Cardiovascular and Stroke Nursing; Council on Clinical Cardiology. Guidelines for the Management of spontaneous intracerebral hemorrhage: a guideline for healthcare professionals from the American Heart Association/American Stroke Association. Stroke 2015; 46:2032-2060.
- Boulouis G, Morotti A, Pasi M, Goldstein JN, Gurol ME, Charidimou A. Outcome of intracerebral haemorrhage related to non-vitamin K antagonists oral anticoagulants versus vitamin K antagonists: a comprehensive systematic review and meta-analysis. JNNP 2018; 89:263-270.
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