Neuropsychiatric systemic lupus erythematosus (NPSLE): clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Neuropsychiatric systemic lupus erythematosus (NPSLE): clinical features. Headache, Seizures. Fully referenced neurology checklist.
Cerebral features
- Headache
- Seizures
- Acute confusional state
- Cerebrovascular disease
- Cognitive dysfunction
Inflammatory and immune features
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Psychiatric features
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Peripheral features
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Differential diagnosis
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References
- Zhou HQ, Zhang FC, Tian XP, et al. Clinical features and outcome of neuropsychiatric lupus in Chinese: analysis of 240 hospitalized patients. Lupus 2008; 17:93-99.
- Jain S, Khormi A, Sangle SR, D’Cruz DP. Transverse myelitis associated with systemic lupus erythematosus (SLE-TM): a review article. Lupus 2023; 32:1033-1042.
- Raciborska DD, Noyce AJ, Pyne D, Turner BP. Lupus myelopathy. Pract Neurol 2018; 18:66-69.
- Budhram A, Butendieck RR, Duarte-Garcia A, Brinjikji W, Zalewski NL. Striatal encephalitis: potential inflammatory vasculopathy in systemic lupus erythematosus. Can J Neurol Sci 2020 (Online ahead of print).
- Munhoz RP, Fameli H, Teive HA. Stiff person syndrome as the initial manifestation of systemic lupus erythematosus. Mov Disord 2010; 25:516-517.
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