Neuromyotonia: clinical features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Neuromyotonia: clinical features. Cramps, Pseudomyotonia, Myokymia, Excessive sweating, Paraesthesias, Mild weakness. Fully referenced neurology checklist.

Peripheral features

  • Cramps
  • Pseudomyotonia
  • Myokymia
  • Excessive sweating
  • Paraesthesias
  • Mild weakness
  • Muscle hypertrophy
  • Painless involuntary flexion of ring and middle fingers
  • Armadillo syndrome (laborious gait)
  • Finger flexion
  • Clenched fists
  • Prolonged paralysis after general anaesthesia

Central features

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Differential diagnosis

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Synonym

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References

  1. Maddison P. Neuromyotonia. Clinl Neurophysiol 2006; 117:2118-2127.
  2. Modarres H, Samuel M, Schon F. Isolated finger flexion: a novel form of focal neuromyotonia. JNNP 2000; 69:110-113.
  3. Ropper AH, Brown RH. Principles of Neurology. Eigth edition. McGraw Hill New York 2005 p1278.
  4. Jamora RD, Umapathi T, Tan LC. Finger flexion resembling focal dystonia in Isaacs' syndrome. Parkinsonism Relat Disord 2006; 12:61-63. 
  5. Dhanapalaratnam R, Schwartz R, Huynh W. Teaching Video NeuroImage: Clenched fists as an unusual presentation of focal neuromyotonia. Neurology 2021; 97:e429-e430.
  6. And 2 more. Subscribe to see the full list

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