Morvan's syndrome
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Morvan's syndrome. This is usually associated with CASPR2 antibody. It may be antibody-negative. Fully referenced neurology checklist.
Aetiology
- This is usually associated with CASPR2 antibody
- It may be antibody-negative
Neurological features
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Systemic features
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Differential diagnosis
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Treatment
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References
- Liguori R, Vincent A, Clover L, et al. Morvan's syndrome: peripheral and central nervous system and cardiac involvement with antibodies to voltage-gated potassium channels. Brain 2001; 124:2417-2426.
- Vincent A, Bien CG, Irani S, Waters P. Autoantibodies associated with diseases of the CNS: new developments and future challenges. Lancet Neurol 2011; 10:759-772.
- Toosy AT, Burbridge SE, Pitkanen M, et al. Functional imaging correlates of fronto-temporal dysfunction in Morvan's syndrome. JNNP 2008; 79:734.
- Maskery M, Chhetri SK, Dayanandan R, Gall C, Emsley HC. Morvan syndrome: a case report with patient narrative and video. Neurohospitalist 2016; 6:32-35.
- Nawfal O, Agha M, Makki A, Beydoun A. Refractory Morvan syndrome responsive to rituximab: a case report and review of the literature. Neuromuscul Disord 2022; 32:682-686.