Myasthenic crisis: management
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Myasthenic crisis: management. Intravenous immunoglobulin (IVIg). Fully referenced neurology checklist.
Immunological management
- Intravenous immunoglobulin (IVIg)
- Plasma exchange (PE): this is probably better than IVIg
- Prednisolone
- Ciclosporin for long-term treatment: it is quicker acting than Azathioprine or Mycophenolate
- Thymectomy: when the patient is stable
Respiratory management
Locked: subscribe to see this section.
Nutritional management
Locked: subscribe to see this section.
Medical management
Locked: subscribe to see this section.
Predictors of ventilatory failure: the 20/30/40 rule
Locked: subscribe to see this section.
References
- Godoy DA, Mello LJ, Masotti L, Napoli MD. The myasthenic patient in crisis: an update of the management in Neurointensive Care Unit. Arq Neuropsiquiatr 2013; 71:627-639.
- Chaudhuri A, Behan PO. Myasthenic crisis. Q J Med 2009; 102:97-107.
- Wendell LC, Levine JM. Myasthenic crisis. Neurohospitalist 2011; 1:16-22.
- Claytor B, Cho SM, Li Y. Myasthenic crisis. Muscle Nerve 2023; 68:8-19.
