Myasthenia gravis (MG): cholinergic crisis
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Myasthenia gravis (MG): cholinergic crisis. This is respiratory failure caused by cholinergic excess. Fully referenced neurology checklist.
Description
- This is respiratory failure caused by cholinergic excess
- It is caused by cholinesterase inhibitors
Neurological features
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Systemic features
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Investigation: Edrophonium test: benefit
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Differential diagnosis: other causes of cholinergic crisis
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Treatment
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References
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References
- Hetherington KA, Losek JD. Myasthenia gravis: myasthenia vs. cholinergic crisis. Pediatr Emerg Care 2005; 21:546-548.
- Wendell LC, Levine JM. Myasthenic crisis. Neurohospitalist 2011; 1:16-22.
- Godoy DA, Mello LJ, Masotti L, Napoli MD. The myasthenic patient in crisis: an update of the management in Neurointensive Care Unit. Arq Neuropsiquiatr 2013; 71(9A):627-639.
- Waseem M, Perry C, Bomann S, Pai M, Gernsheimer J. Cholinergic crisis after rodenticide poisoning. West J Emerg Med 2010; 11:524-527.
- Azazh A. Severe organophosphate poisoning with delayed cholinergic crisis, intermediate syndrome and organophosphate induced delayed polyneuropathy on succession. Ethiop J Health Sci 2011; 21:203-208.
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