Myasthenia gravis (MG): classification
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Myasthenia gravis (MG): classification. This is usually in females. Age at onset is<50 years. Fully referenced neurology checklist.
Early-onset MG with acetylcholine receptor antibodies
- This is usually in females
- Age at onset is<50 years
- It is associated with thymic hyperplasia
Late-onset MG with acetylcholine receptor antibodies
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MUSK associated MG
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LRP4 associated MG
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Seronegative MG
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Thymoma associated MG
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Ocular MG
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Other MG types
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Acronyms
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References
- Gilhus NE, Verschuuren JJ. Myasthenia gravis: subgroup classification and therapeutic strategies. Lancet Neurol 2015; 14:1023-1036.
- Jayam Trouth A, Dabi A, Solieman N, Kurukumbi M, Kalyanam J. Myasthenia gravis: a review. Autoimmune Dis 2012; 2012:874680.
- Gilhus NE, Owe JF, Hoff JM, Romi F, Skele GO, Aarli JA. Myasthenia gravis: a review of available treatment approaches. Autoimmune Dis 2011; 10:1-6.
- Sieb JP. Myasthenia gravis: an update for the clinician. Clin Exp Immunol 2014; 175:408-418.
- Mergenthaler P, Stetefeld HR, Dohmen C, et al. Seronegative myasthenic crisis: a multicenter analysis. J Neurol 2022; 269:3904-3911.
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