Mpox: management
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Mpox: management. Diffuse cerebral oedema, Meningeal enhancement. Fully referenced neurology checklist.
Magnetic resonance imaging (MRI)
- Diffuse cerebral oedema
- Hyperintensity in the thalamus, brainstem and posterior parietal cortex
- Meningeal enhancement
- Longitudinally extensive central spinal cord lesions
Cerebrospinal fluid (CSF) analysis
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Electroencephalogram (EEG)
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Other investigations
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Treatment
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Predictors of severe disease
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References
- Badenoch JB, Conti I, Rengasamy ER, et al. Neurological and psychiatric presentations associated with human monkeypox virus infection: a systematic review and meta-analysis. EClinicalMedicine 2022; 52:101644.
- Samaranayake L, Anil S. The monkeypox outbreak and implications for dental practice. Int Dent J 2022; 72:589-596.
- Hasan S, Saeed S. Monkeypox disease: an emerging public health concern in the shadow of COVID-19 pandemic: an update. Trop Med Infect Dis 2022; 7:283.
- Sepehrinezhad A, Ashayeri Ahmadabad R, Sahab-Negah S. Monkeypox virus from neurological complications to neuroinvasive properties: current status and future perspectives. J Neurol 2022 (Online ahead of print).
- Pastula DM, Tyler KL. An overview of monkeypox virus and its neuroinvasive potential. Ann Neurol 2022; 92:527-531.
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