Motor neurone diseases (MND): gastrostomy
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Motor neurone diseases (MND): gastrostomy. It stabilises weight and prolongs survival in about 50% of patients. Fully referenced neurology checklist.
Percutaneous endoscopic gastrostomy (PEG)
- It stabilises weight and prolongs survival in about 50% of patients
- The best outcomes are with young-onset age
- It is indicated when there is a 10% loss in baseline weight (but 5% has been suggested)
- It is also helpful when there is a doubling of eating time
- Recurrent cough and choking at meals also indicate the need for a PEG
- It is only performed if the forced vital capacity (FVC) is ≥ 50%
Radiologically inserted gastrostomy (RIG)
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References
- ProGas Study Group. Gastrostomy in patients with amyotrophic lateral sclerosis (ProGas): a prospective cohort study. Lancet Neurol 2015; 14:702-709.
- Leigh PN, Abrahams S, Al-Chalabi A, et al. The management of motor neurone disease. JNNP 2003; 74(Suppl IV):iv32-iv47.
- Falcão de Campos C, de Carvalho M. Riluzole-induced recurrent pancreatitis. J Clin Neurosci 2017; 45:153-154.