Motor neurone disease (MND): non-invasive ventilation (NIV)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Motor neurone disease (MND): non-invasive ventilation (NIV). To prevent respiratory decompensation. Fully referenced neurology checklist.
Indications
- To prevent respiratory decompensation
- To alter chest wall and lung growth characteristics
- To monitor the perioperative period
- For PEG placement
- During pregnancy
- To rest respiratory muscles
- To control nocturnal hypoventilation
- To treat hypercapnic respiratory failure
- To palliate symptoms at end of life
Benefits
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Home monitoring indices
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Indications for invasive ventilation with tracheostomy
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References
- Simonds AK. Recent advances in respiratory care for neuromuscular disease. Chest 2006; 130:1879-1886.
- Motor neurone disease: The use of non-invasive ventilation in the management of motor neurone disease. NICE guideline [CG105] July 2010.
- Eng D. Management guidelines for motor neurone disease patients on non-invasive ventilation at home. Palliat Med 2006; 20:69-79.
- Grassano M, Koumantakis E, Manera U, et al. Giving breath to motor neurons: noninvasive mechanical ventilation slows disease progression in amyotrophic lateral sclerosis. Ann Neurol 2024; 95:817-822.
- Miller RG, Jackson CE, Kasarskis EJ, et al. Practice parameter update: the care of the patient with amyotrophic lateral sclerosis: drug, nutritional, and respiratory therapies (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology 2009; 73:1218-1226.
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