Motor neurone disease (MND): MRI features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Motor neurone disease (MND): MRI features. There is thinning of primary motor cortex. Fully referenced neurology checklist.

Cerebral atrophy

  • There is thinning of primary motor cortex
  • There is thinning of the parietal and temporal cortex
  • There is precentral and corpus callosum atrophy

Other brain abnormalities

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Muscle abnormalities

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Spine abnormalities

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Muscle ultrasound

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Acronym

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References

  1. Wood-Allum C, Shaw PJ. Motor neurone disease: a practical update on diagnosis and management. Clin Med 2010; 10:252-258.
  2. Sawalha K, Gonzalez-Toledo E, Hussein O. Role of magnetic resonance imaging in diagnosis of motor neuron disease: literature review and two case illustrations. Perm J 2019; 23. pii:18-131.
  3. Verstraete E, Veldink JH, Hendrikse J, Schelhaas HJ, van den Heuvel MP, van den Berg LH. Structural MRI reveals cortical thinning in amyotrophic lateral sclerosis. JNNP 2012; 83:383-388.
  4. Tartaglia MC, Laluz V, Rowe A, et al. Brain atrophy in primary lateral sclerosis. Neurology 2009; 72:1236-1241.
  5. Turner MR, Modo M. Advances in the application of MRI to amyotrophic lateral sclerosis. Expert Opin Med Diagn 2010; 4:483–496.
  6. And 12 more. Subscribe to see the full list

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