Moebius syndrome: neurological features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Moebius syndrome: neurological features. Bilateral facial weakness (facial diplegia), Inability to smile. Fully referenced neurology checklist.

Facial abnormalities

  • Bilateral facial weakness (facial diplegia)
  • Inability to smile
  • Inability to shut the mouth when eating
  • Difficulty sucking

Movement disorders

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Central respiratory impairment

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Other neurological features

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References

  1. Singham J, Manktelow R, Zuker RM. Möbius syndrome. Semin Plast Surg 2004; 18:39-46. 
  2. Kumar D. Moebius syndrome. J Med Genet. 1990; 27:122-126.
  3. Webb BD, Frempong T, Naidich TP, Gaspar H, Jabs EW, Rucker JC. Mirror movements identified in patients with moebius syndrome. Tremor Other Hyperkinet Mov (N Y) 2014; 4:256. 
  4. Bonanni P, Guerrini R. Segmental facial myoclonus in moebius syndrome. Mov Disord 1999; 14:1021-1024.
  5. Gilmore RL, Falace P, Kanga J, Baumann R. Sleep-disordered breathing in Möbius syndrome. J Child Neurol 1991; 6:73-77.
  6. And 13 more. Subscribe to see the full list

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