Migraine prophylaxis: botulinum toxin
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Migraine prophylaxis: botulinum toxin. Chronic migraine: it is effective, safe and well-tolerated. Fully referenced neurology checklist.
Indications
- Chronic migraine: it is effective, safe and well-tolerated
- Failure of 2-3 previous migraine prophylactic drugs
Muscles injected
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Procedure: PREMT injection protocol
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Indicators of response
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Indications to stop treatment
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References
- Blumenfeld A, Silberstein SD, Dodick DW, Aurora SK, Turkel CC, Binder WJ. Method of injection of onabotulinumtoxin A for chronic migraine: a safe, well-tolerated, and effective treatment paradigm based on the PREEMPT clinical program. Headache 2010; 50:1406-1418.
- Bendtsen L, Sacco S, Ashina M, et al. Guideline on the use of onabotulinumtoxinA in chronic migraine: a consensus statement from the European Headache Federation. J Headache Pain 2018; 19:91.
- Diener HC, Dodick DW, Turkel CC, et al. Pooled analysis of the safety and tolerability of onabotulinumtoxinA in the treatment of chronic migraine. Eur J Neurol 2014; 21:851-859.
