Meningiomas: risk factors
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Meningiomas: risk factors. Neurofibromatosis type 2 (NF2), Multiple endocrine neoplasia type 1 (MEN1). Fully referenced neurology checklist.
Major tumour syndromes
- Neurofibromatosis type 2 (NF2)
- Multiple endocrine neoplasia type 1 (MEN1)
Copy number alterations (CNAs)
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Major cancer predisposition mutations
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Other cancer predisposition mutations
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Epigenomic alterations: DNA methylation
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Epigenomic alterations: micro RNA
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Hormonal risk factors
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Environmental risk factors
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References
- Wiemels J, Wrensch M, Claus EB. Epidemiology and etiology of meningioma. J Neurooncol 2010; 99:307-314.
- Rogers L, Barani I, Chamberlain M, et al. Meningiomas: knowledge base, treatment outcomes, and uncertainties. A RANO review. J Neurosurg 2015; 122:4-23.
- Nigim F, Wakimoto H, Kasper EM, Ackermans L, Temel Y. Emerging medical treatments for meningioma in the molecular era. Biomedicines 2018; 6(3) pii: E86.
- Claus EB, Calvocoressi L, Bondy ML, Wrensch M, Wiemels JL, Schildkraut JM. Exogenous hormone use, reproductive factors, and risk of intracranial meningioma in females. J Neurosurg 2013; 118:649-656.
- Suppiah S, Nassiri F, Bi WL, et al; International Consortium on Meningiomas. Molecular and translational advances in meningiomas. Neuro Oncol 2019; 21(Supplement_1):i4-i17.
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