Lithium toxicity: risk factors
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Lithium toxicity: risk factors. Older age, Physical illness: with diarrhoea and vomiting, Renal impairment. Fully referenced neurology checklist.
Medical risk factors
- Older age
- Physical illness: with diarrhoea and vomiting
- Renal impairment
- Schizophrenia
- Rapid Stroke
- Bariatric surgery
- Correction of hyponatraemia
Drug-interaction risk factors
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References
- Newman PK, Saunders M. Lithium neurotoxicity. Postgrad Med J 1979; 55:701-703.
- Suraya Y, Yoong KY. Lithium neurotoxicity. Med J Malaysia 2001; 56:378-381.
- Moskowitz AS, Altshuler L. Increased sensitivity to lithium-induced neurotoxicity after stroke: a case report. J Clin Psychopharmacol 1991; 11:272-273.
- Musfeldt D, Levinson A, Nykiel J, Carino G. Lithium toxicity after Roux-en-Y bariatric surgery. BMJ Case Rep 2016; pii: bcr2015214056.
- Roy M, Stip E, Black D, Lew V, Langlois R. Cerebellar degeneration following acute lithium intoxication. Rev Neurol (Paris) 1998; 154:546-548.
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