KLHL11 paraneoplastic encephalitis: pathology
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
KLHL11 paraneoplastic encephalitis: pathology. KLHL is Kelch-like protein 11. Fully referenced neurology checklist.
Pathology
- KLHL is Kelch-like protein 11
- It causes autoimmune encephalitis: mainly cerebellar
HLA associations
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Associated tumours
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Overlapping antibodies
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References
- Maudes E, Landa J, Muñoz-Lopetegi A, et al. Clinical significance of Kelch-like protein 11 antibodies. Neurol Neuroimmunol Neuroinflamm 2020; pii: e666.
- Wong JK, Yu J, Patterson A, Carlson A, Wagle Shukla A. Clinical and imaging features of newly recognized Kelch-like protein 11 paraneoplastic syndrome. Neurology 2020; 95:134-135.
- Dubey D, Wilson MR, Clarkson B, et al. Expanded clinical phenotype, oncological associations, and immunopathologic insights of paraneoplastic Kelch-like protein-11 encephalitis. JAMA Neurol 2020 (Online ahead of print).
- Song Y, Hu Q, Zhang Q. Anti-Kelch-like protein 11 antibody encephalitis: a case report and literature review. Front Neurol 2023; 14:1273051.
- Dubey D, Wilson MR, Clarkson B, et al. Expanded clinical phenotype, oncological associations, and immunopathologic insights of paraneoplastic kelch-like protein-11 encephalitis. JAMA Neurol 2020; 77:1420-1429.
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