Kawasaki disease: systemic features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Kawasaki disease: systemic features. This is an acute febrile systemic vasculitis. Fully referenced neurology checklist.

Pathology

  • This is an acute febrile systemic vasculitis
  • It is possibly of infective aetiology
  • It is IgA mediated
  • ITPKC is a possible susceptibility gene
  • It has been associated with SARS-Cov-2 (COVID) infection

Epidemiology

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Diagnostic features

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Clinical phases

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Constitutional features

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Cardiac features

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Dermatological features

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Gastrointestinal features

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Ophthalmic features

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Other features

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Synonym

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References

  1. Rowley AH, Shulman ST. Recent advances in the understanding and management of Kawasaki disease. Curr Infect Dis Rep 2010; 12:96-102.
  2. Kim DS. Kawasaki disease. Yonsei Med J 2006; 47:759-772.
  3. Rowley AH, Shulman ST. Pathogenesis and management of Kawasaki disease. Expert Rev Anti Infect Ther 2010; 8:197-203.
  4. Godfred-Cato S, Bryant B, Leung J, et al. COVID-19-associated multisystem inflammatory syndrome in children - United States, March-July 2020. MMWR Morb Mortal Wkly Rep 2020; 69:1074-1080.
  5. Ahmed M, Advani S, Moreira A, et al. Multisystem inflammatory syndrome in children: a systematic review. EClinicalMedicine 2020 (Online ahead of print).
  6. And 20 more. Subscribe to see the full list

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