Kawasaki disease: management
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Kawasaki disease: management. Leukocytosis, Anaemia, Raised erythrocyte sedimentation rate (ESR). Fully referenced neurology checklist.
Laboratory features
- Leukocytosis
- Anaemia
- Raised erythrocyte sedimentation rate (ESR)
- Raised C-reactive protein (CRP)
- Increased platelet count
- Increased transaminases
- Low serum protein (hypoalbulinaemia)
- Reduced plasma cholesterol
- Reduced high-density lipoprotein (HDL)
- Reduced apolipoprotein A-I
Cerebrospinal fluid (CSF) analysis
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Other investigations
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Acute treatment: Aspirin
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Acute treatment: intravenous immunoglobulins (IVIg)
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Treatment of refractory disease: adjunctive options
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Treatment of severe disease: anti-thrombotic options
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Synonym
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Acronym
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References
- Rowley AH, Shulman ST. Recent advances in the understanding and management of Kawasaki disease. Curr Infect Dis Rep 2010; 12:96-102.
- Kim DS. Kawasaki disease. Yonsei Med J 2006; 47:759-772.
- Rowley AH, Shulman ST. Pathogenesis and management of Kawasaki disease. Expert Rev Anti Infect Ther 2010; 8:197-203.
- Eleftheriou D, Levin M, Shingadia D, Tulloh R, Klein NJ, Brogan PA. Management of Kawasaki disease. Arch Dis Child 2014; 99:74-83.
- Melish ME. Kawasaki syndrome (the mucocutaneous lymph node syndrome). Annu Rev Med 1982; 33:569-585.
