Juvenile myoclonic epilepsy (JME)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Juvenile myoclonic epilepsy (JME). The onset age is typically 12-18 years. It may start as late as the 8th decade. Fully referenced neurology checklist.
Epidemiology
- The onset age is typically 12-18 years
- It may start as late as the 8th decade
- There is a positive family history in about 50% of cases
Myoclonic features
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Reflex features
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Other seizure types
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Triggers for seizures
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Cognitive features
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Adult onset features
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Risk factors for refractory JME
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Electroencephalogram (EEG): features
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Treatment
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Contraindicated treatments which induce myoclonus
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Contraindicated treatments which worsen seizures
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Synonym
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References
- Renganathan R, Delanty N. Juvenile myoclonic epilepsy: under-appreciated and under-diagnosed. Postgrad Med J 2003; 79:78-80.
- Nicolson A, Chadwick DW, Smith DF. A comparison of adult onset and "classical" idiopathic generalised epilepsy. JNNP 2004; 75:72-74.
- Reichsoellner J, Larch J, Unterberger I, et al. Idiopathic generalised epilepsy of late onset: a separate nosological entity? JNNP 2010; 81:1218-1222.
- Toth V, Rasonyi G, Fogarasi A, Kovaks N, Auer T, Janszky J. Juvenile myoclonic epilepsy starting in the eighth decade. Epileptic Disord 2007; 9:341-345.
- Uchida CG, de Carvalho KC, Guaranha MS, et al. Phenotyping juvenile myoclonic epilepsy. Praxis induction as a biomarker of unfavorable prognosis. Seizure 2015; 32:62-68.
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