Hereditary neuralgic amyotrophy (HNA)
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Hereditary neuralgic amyotrophy (HNA). This is caused by mutations in the SEPTIN9 gene. Fully referenced neurology checklist.
Genetics
- This is caused by mutations in the SEPTIN9 gene
- The transmission is autosomal dominant
- It has an early age of onset
Clinical features
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Dysmorphic features
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Differentiating features from acquired neuralgic amyotrophy
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References
- van Alfen N. The neuralgic amyotrophy consultation. J Neurol 2007; 254:695-704.
- Santana L, Amparo Gutierrez A. Neuralgic amyotrophy. Curr Treat Options Neurol 2009; 11:85–89.
- Gonzalez-Alegre P, Recober A, Kelkar P. Idiopathic brachial neuritis. Iowa Orthop J 2002; 22:81-85.
- Theuriet J, Quadrio I, Fer F, et al. Clinical features and prognosis of SEPTIN9-related hereditary neuralgic amyotrophy. Eur J Neurol 2026; 33:e70603.
