Guillain Barre syndrome (GBS): diagnostic criteria

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Guillain Barre syndrome (GBS): diagnostic criteria. There is bilateral flaccid weakness. Fully referenced neurology checklist.

Brighton GBS diagnostic criteria

  • There is bilateral flaccid weakness
  • There are reduced or absent reflexes in the weak limbs
  • It follows a monophasic course from 12 hours to 28 days
  • The cerebrospinal fluid (CSF) cell count is <50/mL
  • There is raised CSF protein
  • There are consistent nerve conduction studies (NCS)
  • There are no alternative causes

References

  1. Fokke C, van den Berg B, Drenthen J, Walgaard C, van Doorn PA, Jacobs BC. Diagnosis of Guillain Barre syndrome and validation of Brighton criteria. Brain 2014; 137:33-43.
  2. Asbury AK, Cornblath DR. Assessment of current diagnostic criteria for Guillain-Barre syndrome. Ann Neurol 1990; 27(Suppl):S21-S24.

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