Guillain Barre syndrome (GBS): clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Guillain Barre syndrome (GBS): clinical features. Progressive weakness: this is predominantly proximal, Hypotonia. Fully referenced neurology checklist.
Peripheral features
- Progressive weakness: this is predominantly proximal
- Hypotonia
- Reduced reflexes
- Facial weakness
- Ophthalmoplegia
- Severe fatigue: in about 80% of cases
- Autonomic dysfunction
Pain
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Psychiatric features
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Cranial nerve features
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Other features
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Unusual presentations
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Red flags against GBS
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References
- Hughes RAC, Rees JH. Clinical and epidemiologic features of Guillain-Barre syndrome. J Infect Dis 1997; 176(Suppl 2):S92-S98.
- Ruts L, Drenthen J, Jongen JLM, et al. Pain in Guillain Barre syndrome: a long-term follow up study. Neurology 2010; 75:1439-1447.
- Moulin DE, Hagen N, Feasby TE, Amireh R, Hahn A. Pain in Guillain Barre syndrome. Neurology 1997; 48:328-331.
- Wu X, Shen D, Li T, Zhang B, Li C, Mao M, Zhao J, Liu K, Zhang HL. Distinct clinical characteristics of pediatric Guillain-Barre syndrome: a comparative study between children and adults in Northeast China. PLoS One 2016; 11:e0151611.
- Cochen V, Arnulf I, Demeter S, et al. Vivid dreams, hallucinations, psychosis and REM sleep in Guillain-Barre syndrome. Brain 2005; 128:2535-2545.
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