Gasoline toxicity
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Gasoline toxicity. Toxicity is related to the lead and hydrocarbon components of gasoline. Fully referenced neurology checklist.
Pathology and toxicity
- Toxicity is related to the lead and hydrocarbon components of gasoline
- Toxicity develops after 15-20 inhalations
- It can last up to 6 hours
Modes of inhalation
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Risk groups
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Acute toxicity
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Chronic toxicity: central features
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Chronic toxicity: peripheral features
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Investigations
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Treatment: lead chelation therapy
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Synonym
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References
- Cairney S, Maruff P, Burns C, Currie B. The neurobehavioural consequences of petrol (gasoline) sniffing. Neurosci Biobehav Rev 2002; 26:81-89.
- Hestnes A, Sand T, Leira HL. Polyneuropathy in gasoline workers. Tidsskr Nor Laegeforen 1987; 107:1031-1032.
- Maruff P, Burns CB, Tyler P, Currie BJ, Currie J. Neurological and cognitive abnormalities associated with chronic petrol sniffing. Brain 1998; 121:1903-1917.
- Cairney S, Maruff P, Burns CB, Currie J, Currie BJ. Saccade dysfunction associated with chronic petrol sniffing and lead encephalopathy. JNNP 2004; 75:472-476.
- Goodheart RS, Dunne JW. Petrol sniffer's encephalopathy. A study of 25 patients. Med J Aust 1994; 160:178-181.
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