Cannabis (marijuana) toxicity
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Cannabis (marijuana) toxicity. The active compound is δ-9-tetrahydrocannabinol. It is taken by inhalation or orally. Fully referenced neurology checklist.
Chemistry
- The active compound is δ-9-tetrahydrocannabinol
- It is taken by inhalation or orally
Acute neurological features
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Acute cardiovascular features
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Acute systemic features
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Chronic neurological features
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Cannabis withdrawal features
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Magnetic resonance imaging (MRI) brain
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References
- Geibprasert S, Gallucci M, Krings T. Addictive illegal drugs: structural neuroimaging. AJNR Am J Neuroradiol 2010; 31:803-808.
- Burggren AC, Shirazi A, Ginder N, London ED. Cannabis effects on brain structure, function, and cognition: considerations for medical uses of cannabis and its derivatives. Am J Drug Alcohol Abuse 2019; 45:563-579.
- Kesner AJ, Lovinger DM. Cannabis use, abuse, and withdrawal: cannabinergic mechanisms, clinical, and preclinical findings. J Neurochem 2021; 157:1674-1696.
- Zehra A, Burns J, Liu CK, Manza P, Wiers CE, Volkow ND, Wang GJ. Cannabis addiction and the brain: a review. J Neuroimmune Pharmacol 2018; 13:438-452.
- Yücel M, Solowij N, Respondek C, et al. Regional brain abnormalities associated with long-term heavy cannabis use. Arch Gen Psychiatry 2008; 65:694-701.
