Epilepsy: seizure control

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Epilepsy: seizure control. Seizure control is achieved in 50% of cases with the first AED. Fully referenced neurology checklist.

Seizure control rate

  • Seizure control is achieved in 50% of cases with the first AED
  • It is achieved in 30% with the second AED
  • Eventual seizure control is achieved in about 20% of initially pharmaco-resistant cases

Seizure recurrence rate

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Risk factors for seizure recurrence

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Indications for specialist referral in poor seizure control

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References

  1. Perucca E, Tomson T. The pharmacological treatment of epilepsy. Lancet Neurol 2011; 10:446-456.
  2. Seneviratne U. Management of the first seizure: an evidence based approach. Postgrad Med J 2009; 85:667-673.
  3. Hixson JD. Stopping antiepileptic drugs: when and why? Curr Treat Options Neurol 2010; 12:434-442.
  4. Berg AT, Shinnar S. Relapse following discontinuation of antiepileptic drugs: a meta-analysis. Neurology 1994; 44:601-608.
  5. Lossius MI, Hessen E, Mowinckel P, et al. Consequences of antiepileptic drug withdrawal: a randomized, double-blind study. Epilepsia 2008; 3:455-463.
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