Epilepsy remission
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Epilepsy remission. 5 years of seizure-freedom, The last 2 years should be off medications. Fully referenced neurology checklist.
Definition of remission
- 5 years of seizure-freedom
- The last 2 years should be off medications
Proposed re-definition of remission
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Frequency of achieving remission
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Predictors of spontaneous remission
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Predictors of treatment remission
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Predictors of failure to achieve remission
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References
- Kwan P, Sander JW. The natural history of epilepsy: an epidemiological view. JNNP 2004; 75:1376-1381.
- Sillanpää M, Schmidt D, Saarinen MM, Shinnar S. Remission in epilepsy: how long is enough? Epilepsia 2017; 58:901-906.
- Shorvon SD, Goodridge DM. Longitudinal cohort studies of the prognosis of epilepsy: contribution the National General Practice Study of Epilepsy and other studies. Brain 2013; 136:3497-3510.
- Giussani G, Canelli V, Bianchi E, et al; EPIRES Group. Long-term prognosis of epilepsy, prognostic patterns and drug resistance: a population-based study. Eur J Neurol 2016; 23:1218-1227.
- Annegers JF, HauserWA, Elveback LR. Remission of seizures and relapse in patients with epilepsy. Epilepsia 1979; 20:729–737.
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