Ependymoma: grading and pathology
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Ependymoma: grading and pathology. Ependymomas are tumours arising from the ventricular lining. Fully referenced neurology checklist.
Pathology
- Ependymomas are tumours arising from the ventricular lining
- They originate from radial glial stem cells
Grade I
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Grade II
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Grade III
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Classification by location
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References
- Rudà R, Reifenberger G, Frappaz D, et al. EANO guidelines for the diagnosis and treatment of ependymal tumors. Neuro Oncol 2018; 20:445-456.
- Sartor EA, Wen PY. Adjuvant treatments for ependymomas. J Neurosurg Sci 2018; 62:71-77.
- Pajtler KW, Witt H, Sill M, et al. Molecular classification of ependymal tumors across all CNS compartments, histopathological grades, and age groups. Cancer Cell 2015; 27:728-743.
- Wang M, Zhang R, Liu X, et al. Supratentorial cortical ependymomas: a retrospective series of 13 cases at a single center. World Neurosurg 2018; 112:e772-e777.
- Van Gompel JJ, Koeller KK, Meyer FB, et al. Cortical ependymoma: an unusual epileptogenic lesion. J Neurosurg 2011; 114:1187-1194.
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