Diabetic neuropathy: investigations

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Diabetic neuropathy: investigations. There is a high frequency of MGUS in diabetic neuropathy. Fully referenced neurology checklist.

Immunoglobulins

  • There is a high frequency of MGUS in diabetic neuropathy
  • This is usually in the form of IgM and IgG

Autonomic function tests

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Nerve function tests

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Corneal confocal microscopy (CCM)

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Acronym

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References

  1. Tavakoli M, Petropoulos IN, Malik RA. Corneal confocal microscopy to assess diabetic neuropathy: an eye on the foot. J Diabetes Sci Technol 2013; 7:1179-1189.
  2. Abraham A, Barnett C, Katzberg HD, Lovblom LE, Perkins BA, Bril V. High frequency of MGUS in DSP. Muscle Nerve 2018; 57:1018-1021. 
  3. Tavakoli M, Mitu-Pretorian M, Petropoulos IN, et al. Corneal confocal microscopy detects early nerve regeneration in diabetic neuropathy after simultaneous pancreas and kidney transplantation. Diabetes 2013; 62:254-260.
  4. Dhage S, Ferdousi M, Adam S, et al. Corneal confocal microscopy identifies small fibre damage and progression of diabetic neuropathy. Sci Rep 2021; 11:1859.

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