Cytotoxic lesions of the corpus callosum (CLOCC): causes

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Cytotoxic lesions of the corpus callosum (CLOCC): causes. Carbamazepine: both use and withdrawal, Phenytoin. Fully referenced neurology checklist.

Drug-induced causes

  • Carbamazepine: both use and withdrawal
  • Phenytoin
  • Vigabatrin
  • Steroid therapy
  • Ipilimumab
  • Metronidazole

Viral causes

Locked: subscribe to see this section.

Other infectious causes

Locked: subscribe to see this section.

Metabolic causes

Locked: subscribe to see this section.

Autoimmune causes

Locked: subscribe to see this section.

Vascular causes

Locked: subscribe to see this section.

Neoplastic causes

Locked: subscribe to see this section.

Other neurological causes

Locked: subscribe to see this section.

Other systemic causes

Locked: subscribe to see this section.

Synonyms

Locked: subscribe to see this section.

References

  1. Garcia-Monco JC, Cortina IE, Ferreira E, et al. Reversible splenial lesion syndrome (RESLES): what's in a name? J Neuroimaging 2011; 21:e1-e14.
  2. Maeda M, Tsukahara H, Terada H, et al. Reversible splenial lesion with restricted diffusion in a wide spectrum of diseases and conditions. J Neuroradiol 2006; 33:229-236.
  3. Zhu Y, Zheng J, Zhang L, et al. Reversible splenial lesion syndrome associated with encephalitis/encephalopathy presenting with great clinical heterogeneity. BMC Neurol 2016; 16:49. 
  4. Güven H, Delibaş S, Comoğlu SS. Transient lesion in the splenium of the corpus callosum due to carbamazepine. Turk Neurosurg 2008; 18:264-270.
  5. Ruscheweyh R, Marziniak M, Evers S. Reversible focal splenial lesions in facial pain patients treated with antiepileptic drugs: case report and review of the literature. Cephalalgia 2009; 29:587-590. 
  6. And 58 more. Subscribe to see the full list

Related checklists

Loading...