Cramps: treatment

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Cramps: treatment. Quinine: only in selected cases because of toxicity, Vitamin B complex, Naftidrofuryl, Diltiazem. Fully referenced neurology checklist.

Main treatments

  • Quinine: only in selected cases because of toxicity
  • Vitamin B complex
  • Naftidrofuryl
  • Diltiazem
  • Lidocaine

Potentially beneficial treatments

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Open label trials

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References

  1. Katzberg HD, Khan AH, So YT. Assessment: symptomatic treatment for muscle cramps (an evidence-based review): report of the therapeutics and technology assessment subcommittee of the American Academy of Neurology. Neurology 2010; 74:691-696.
  2. Miller TM, Layzer RB. Muscle cramps. Muscle Nerve 2005; 32:431-442.
  3. Guay DR. Are there alternatives to the use of quinine to treat nocturnal leg cramps? Consult Pharm 2008; 23:141-156.
  4. Ropper AH, Brown RH. Principles of Neurology. Eighth edition. McGraw Hill New York 2005 p1276.

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