Corticobasal syndrome (CBS): pathology

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Corticobasal syndrome (CBS): pathology. The onset age is usually in the 6th and 7th decades. Fully referenced neurology checklist.

Epidemiology

  • The onset age is usually in the 6th and 7th decades
  • There is an equal gender involvement
  • The time course of the syndrome is about 7 years

Major underlying pathologies

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Other neurodegenerative pathologies

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Non-neurodegenerative pathologies

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Genetic mutations

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References

  1. Wilson D, Le Heron C, Anderson T. Corticobasal syndrome: a practical guide. Practical Neurol 2021; 21:276-285.
  2. Parmera JB, Rodriguez RD, Studart Neto A, Nitrini R, Brucki SMD. Corticobasal syndrome: a diagnostic conundrum. Dement Neuropsychol 2016; 10:267-275.
  3. Arienti F, Lazzeri G, Vizziello M, et al. Unravelling genetic factors underlying corticobasal syndrome: a systematic review. Cells 2021; 10:171.
  4. Koga S, Roemer SF, Kasanuki K, Dickson DW. Cerebrovascular pathology presenting as corticobasal syndrome: An autopsy case series of "vascular CBS". Parkinsonism Relat Disord 2019; 68:79-84.
  5. Fuseya K, Kimura A, Yoshikura N, Yamada M, Hayashi Y, Shimohata T. Corticobasal syndrome in a patient with anti-IgLON5 antibodies. Mov Disord Clin Pract 2020; 7:557-559. 
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