Corticobasal syndrome (CBS): investigations
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Corticobasal syndrome (CBS): investigations. MRI: asymmetrical perirolandic cortical atrophy. Fully referenced neurology checklist.
Imaging investigations
- MRI: asymmetrical perirolandic cortical atrophy
- DAT scan: this is usually abnormal
- Amyloid imaging: this may detect AD changes
- PiB-PET scan: this may detect AD changes
- FDG-PET scan: this shows asymmetrical hypometabolism
- SPECT
Neurophysiological investigations
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Cerebrospinal fluid (CSF) analysis
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Acronyms
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References
- Wilson D, Le Heron C, Anderson T. Corticobasal syndrome: a practical guide. Practical Neurol 2021; 21:276-285.
- Parmera JB, Rodriguez RD, Studart Neto A, Nitrini R, Brucki SMD. Corticobasal syndrome: a diagnostic conundrum. Dement Neuropsychol 2016; 10:267-275.
- Bensaïdane MR, Fortin M-P, Damasse G, et al. Clinical utility of amyloid imaging in a complex case of corticobasal syndrome presenting with psychiatric symptoms. J Neurol Disord 2014; 2:1-4.
- Turaga SP, Mridula R, Borgohain R. Cerebral glucose metabolism, clinical, neuropsychological, and radiological profile in patients with corticobasal syndrome. Neurol India 2013; 61:7-11.
- Murgai AA, Jog MS. Neurophysiology and neurochemistry of corticobasal syndrome. J Neurol 2018; 265:991-998.
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