Corticobasal degeneration (CBD): investigations

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Corticobasal degeneration (CBD): investigations. Asymmetrical cortical atrophy, Midbrain atrophy. Fully referenced neurology checklist.

Magnetic resonance imaging (MRI) brain

  • Asymmetrical cortical atrophy
  • Increased signal in the region of maximal atrophy: this is seen on proton density MRI
  • Midbrain atrophy
  • Corpus callosum atrophy
  • The eye of the tiger sign: this has been reported

Cerebrospinal fluid (CSF) analysis

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References

  1. Constantinides VC, Paraskevas GP, Paraskevas PG, Stefanis L, Kapaki E. Corticobasal degeneration and corticobasal syndrome: a review. Clin Park Relat Disord 2019; 1:66-71.

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