Corticobasal degeneration (CBD): clinical features

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Corticobasal degeneration (CBD): clinical features. Corticobasal syndrome (CBS), Frontotemporal dementia (FTD). Fully referenced neurology checklist.

CBD phenotypes

  • Corticobasal syndrome (CBS)
  • Frontotemporal dementia (FTD)
  • Progressive supranuclear palsy (PSP)
  • Posterior cortical atrophy (PCA)
  • Frontal behavioural-spatial syndrome (FBS)
  • Nonfluent/agrammatic variant of primary progressive aphasia (naPPA)
  • Progressive supranuclear palsy (PSP)

Parkinsonian features

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Other movement disorders

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Cortical features

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Behavioural features

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Speech and language features

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Atypical presentations of CBD

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References

  1. Stamelou M, Alonso-Canovss A, Bhatia KP. Dystonia in corticobasal degeneration: a review of the literature on 404 pathologically proven cases. Mov Disord 2012; 27:696-702.
  2. Tolosa E. Parkinson's disease and movement disorders, 5th edition. Lippincott Williams &Wilkins Philadelphia 2007 p186-191.
  3. Armstrong MJ, Litvan I, Lang AE, et al. Criteria for the diagnosis of corticobasal degeneration. Neurology 2013; 80:496–503.
  4. Mathew R, Bak TH, Hodges JR. Diagnostic criteria for corticobasal syndrome: a comparative study. JNNP 2012; 83:405-410.
  5. Rinne JO, Lee MS, Thompson PD, Marsden CD. Corticobasal degeneration. A clinical study of 36 cases. Brain 1994; 117:1183-1196.
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