Coronavirus SARS-CoV-2 infection: systemic investigations

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Coronavirus SARS-CoV-2 infection: systemic investigations. Leukopenia, Lymphopenia, Raised D-dimer. Fully referenced neurology checklist.

Laboratory features

  • Leukopenia
  • Lymphopenia
  • Raised D-dimer
  • Elevated plasminogen level
  • Elevated aspartate aminotransferase
  • Raised interleukins 
  • Elevated hypersensitive troponin I (hs-cTnI): with acute cardiac injury 
  • Elevated procalcitonin: with secondary infections
  • RNAemia (viral load)
  • N-terminal pro-brain natriuretic peptide
  • Hyperkalemia
  • Autoimmune haemolytic anaemia (AIHA)

Chest CT features

Locked: subscribe to see this section.

Virological tests

Locked: subscribe to see this section.

Synonym

Locked: subscribe to see this section.

References

  1. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020; 395:497-506.
  2. Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020; 395:507-513.
  3. Guo YR, Cao QD, Hong ZS, et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak-an update on the status. Mil Med Res 2020; 7:11.
  4. Ji HL, Zhao R, Matalon S, Matthay MA. Elevated plasmin(ogen) as a common risk factor for COVID-19 susceptibility. Physiol Rev 2020; 100:1065-1075.
  5. Chen T, Wu D, Chen H, et al. Clinical characteristics of 113 deceased patients with coronavirus disease 2019: retrospective study. BMJ 2020; 368:m1091.
  6. And 2 more. Subscribe to see the full list

Related checklists

Loading...