Coronavirus SARS-CoV-2 infection: epidemiology and prognosis

Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .

Coronavirus SARS-CoV-2 infection: epidemiology and prognosis. SARS-Cov-2 is a non-segmented positive-sense RNA virus. Fully referenced neurology checklist.

Virology

  • SARS-Cov-2 is a non-segmented positive-sense RNA virus
  • It is a Betacoronavirus of the family Coronaviridae
  • It belongs to the order Nidovirales
  • Bats are possibly the natural hosts: it is 88–96% similar to bat coronaviruses
  • It uses the angiotensin converting enzyme (ACE2) receptor for cell entry

Transmission routes

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Incubation period

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Outcome

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Poor prognostic features

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Synonym

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References

  1. Huang C, Wang Y, Li X, et al. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet 2020; 395:497-506.
  2. Chen N, Zhou M, Dong X, et al. Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study. Lancet 2020; 395:507-513.
  3. Guo YR, Cao QD, Hong ZS, et al. The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak-an update on the status. Mil Med Res 2020; 7:11. 
  4. Lake MA. What we know so far: COVID-19 current clinical knowledge and research. Clin Med (Lond) 2020; 20:124-127. 
  5. Zhang H. Early lessons from the frontline of the 2019-nCoV outbreak. Lancet 2020; 395:687.
  6. And 4 more. Subscribe to see the full list

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