CIDP: investigations
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
CIDP: investigations. Prolonged distal motor latency, Reduced velocities, Prolonged F wave latency. Fully referenced neurology checklist.
Nerve conduction studies (NCS): features
- Prolonged distal motor latency
- Reduced velocities
- Prolonged F wave latency
- Temporal dispersion
- Conduction block
- Slow motor nerve conduction velocity (mNCV): this is <80% of the lower limit
- Sensory NCS is not sensitive
Cerebrospinal fluid (CSF) analysis
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Nerve ultrasound
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Autoantibodies
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Other investigations
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Emerging investigations
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Acronym
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References
- The French CIDP Group, Vallat JM. Recommendations on diagnostic strategies for chronic inflammatory demyelinating polyradiculopathy. Postgrad Med J 2008; 84:378-381.
- The French CIDP Group. Recommendations on diagnostic strategies for chronic inflammatory demyelinating polyradiculopathy. JNNP 2008; 79:115-118.
- Vallat JM, Sommer C, Magy L. Chronic inflammatory demyelinating polyradiculoneuropathy: diagnostic and therapeutic challenges for a treatable condition. Lancet Neurol 2010; 9:402-412.
- Capodivento G, De Michelis C, Carpo M, et al. CSF sphingomyelin: a new biomarker of demyelination in the diagnosis and management of CIDP and GBS. JNNP 2020 (Online ahead of print).
- Grimm A, Schubert V, Axer H, Ziemann U. Giant nerves in chronic inflammatory polyradiculoneuropathy. Muscle Nerve 2017; 55:285-289.
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