Chronic traumatic encephalopathy (CTE): clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Chronic traumatic encephalopathy (CTE): clinical features. This is a progressive neurodegenerative disease. Fully referenced neurology checklist.
Etiology
- This is a progressive neurodegenerative disease
- It is the result of single or repetitive closed head injuries
- The trauma may be sub-concussive
- It is often associated with contact sports
- It is possibly a result of immune-excitotoxicity
Risk factors
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Epidemiological features
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Cognitive features
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Psychiatric features
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Motor features
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Other features
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Differential diagnosis
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References
- Saulle M, Greenwald BD. Chronic traumatic encephalopathy: a review. Rehabil Res Pract 2012; 2012:816069.
- McKee AC, Cantu RC, Nowinski CJ, et al. Chronic traumatic encephalopathy in athletes: progressive tauopathy after repetitive head injury. J Neuropathol Exp Neurol 2009; 68:709-735.
- Baugh CM, Stamm JM, Riley DO, et al. Chronic traumatic encephalopathy: neurodegeneration following repetitive concussive and subconcussive brain trauma. Brain Imaging Behav 2012; 6:244-254.
- McKee AC, Mez J, Abdolmohammadi B. Neuropathologic and clinical findings in young contact sport athletes exposed to repetitive head impacts. JAMA Neurol 2023 (Online ahead of print).
