Cerebral malaria: pathology and clinical features
Written and reviewed by Dr Ibrahim Imam, Consultant Neurologist. Last reviewed .
Cerebral malaria: pathology and clinical features. Cerebral malaria is caused by Plasmodium falciparum (P. falciparum).
Pathology of malaria
- Cerebral malaria is caused by Plasmodium falciparum (P. falciparum)
- It is especially prevalent in sub-Saharan Africa
- It usually affects children
Pathogenesis of cerebral malaria
Locked: subscribe to see this section.
Brainstem features
Locked: subscribe to see this section.
Other neurological features
Locked: subscribe to see this section.
Malarial retinopathy
Locked: subscribe to see this section.
Systemic features
Locked: subscribe to see this section.
Long-term neurocognitive features
Locked: subscribe to see this section.
References
- Idro R, Jenkins NE, Newton CR. Pathogenesis, clinical features, and neurological outcome of cerebral malaria. Lancet Neurol 2005; 4:827-840.
- Newton CR, Hien TT, White N. Cerebral malaria. JNNP 2000; 69:433-441.
- Shikani HJ, Freeman BD, Lisanti MP, Weiss LM, Tanowitz HB, Desruisseaux MS. Cerebral malaria: we have come a long way. Am J Pathol 2012; 181:1484-1492.
- Shabani E, Opoka RO, Idro R, et al. High plasma erythropoietin levels are associated with prolonged coma duration and increased mortality in children with cerebral malaria. Clin Infect Dis 2015; 60:27-35.
- Eisenhut M. Severe hemolysis as a potential contributing factor in the pathophysiology of cerebral malaria. Clin Infect Dis 2015; 60:1138.
- And 9 more. Subscribe to see the full list
